Alien insect species may present a multifaceted threat to ecosystems into which they are introduced.In addition to the direct damage they may cause, they may also bring novel diseases and parasites and/or have the capacity to vector microorganisms that are already established in the ecosystem and are causing harm.Damage caused by ectoparasitic larv
Activating mutations in RAS genes, notably KRASG12C, are pervasive in numerous cancers, presenting formidable challenges to therapy Mirror due to their elusive druggability.The landmark discovery of KRASG12C allosteric inhibitors marked a transformative milestone in cancer treatment, resulting in the approval of sotorasib and adagrasib.However, lim
Description of the subject.The geographic distributions of a species, be it native or alien, is expected to be limited at some point by environmental conditions.In this situation, a range edge equilibrium (REE) takes place, i.e., populations occurring beyond the edge have a growth rate reduced below replacement.The occurrence of REE has never been
This review paper focuses on Fiber-Reinforced Topology Optimization (FRTO) methods for automated manufacturing techniques, addressing topology and morphology optimization.Accordingly, the review introduces the main TO techniques and the common reinforcement path design strategies using concurrent and sequential optimization approaches.Furthermore,